Showing posts with label Hypercortisolism. Show all posts
Showing posts with label Hypercortisolism. Show all posts

Name 6 major clinical signs of Cushing's Disease.

Name 6 major clinical signs of Cushing's Disease.



- PU/PD
- Bilateral truncal alopecia
- Dermal atrophy & fragility
- Muscle atrophy
- Pot belly
- Insulin resistance

Name 3 physiologic mechanisms of PU/PD in a Cushingoid animal.

Name 3 physiologic mechanisms of PU/PD in a Cushingoid animal.



- ADH antagonism/decreased secretion
- Concurrent diabetes mellitus
- Decreased renal tubular water permeability --> decreased water resorption

Cushing's Disease in cats shares a common presentation with another endocrine disease. What is the presentation, what is the other disease, and is there a simple way to distinguish the two?

Cushing's Disease in cats shares a common presentation with another endocrine disease. What is the presentation, what is the other disease, and is there a simple way to distinguish the two?



Answer: Cushing's cats are often diabetic and have severe insulin resistance. The same thing is seen in cats with acromegaly. However, acromegaly is seen mostly in male cats, while Cushing's is seen predominantly in females.